Apom - apolipoprotein M Gene

Mus musculus

Also known as G3a; NG20; 1190010O19Rik

Gene ID: 55938 | Gene type: protein coding

About Apom

Summary

Enables antioxidant activity. Involved in several processes, including Cholesterol efflux; high-density lipoprotein particle clearance; and plasma lipoprotein particle organization. Acts upstream of or within lipoprotein metabolic process and reverse Cholesterol transport. Located in extracellular region. Part of discoidal high-density lipoprotein particle. Is expressed in several structures, including gut; liver; male reproductive gland or organ; and urinary system. Human ortholog(s) of this gene implicated in coronary artery disease; type 1 diabetes mellitus; and type 2 diabetes mellitus. Orthologous to human APOM (apolipoprotein M). [provided by Alliance of Genome Resources, Apr 2022]

Apom Products(1)

mRNA	Protein	Name
NM_018816.2	NP_061286.1	apolipoprotein M precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables antioxidant activity	IDA IDA: Inferred from direct assay	22204862	MGI
enables protein binding	IPI IPI: Inferred from physical interaction	16099815	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cholesterol efflux	IMP IMP: Inferred from mutant phenotype	15793583	MGI
involved in high-density lipoprotein particle assembly	IMP IMP: Inferred from mutant phenotype	15793583	MGI
involved in high-density lipoprotein particle clearance	IMP IMP: Inferred from mutant phenotype	15793583	MGI
involved in high-density lipoprotein particle remodeling	IMP IMP: Inferred from mutant phenotype	15793583	MGI
acts upstream of or within lipoprotein metabolic process	IMP IMP: Inferred from mutant phenotype	15793583	MGI
involved in negative regulation of plasma lipoprotein oxidation	IDA IDA: Inferred from direct assay	22204862	MGI
acts upstream of or within reverse cholesterol transport	IMP IMP: Inferred from mutant phenotype	15793583	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
part of discoidal high-density lipoprotein particle	IDA IDA: Inferred from direct assay	15793583	MGI
located in extracellular region	IDA IDA: Inferred from direct assay	15793583	MGI
part of high-density lipoprotein particle	IDA IDA: Inferred from direct assay	22204862	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

apolipoprotein M

apo-M

Recombinant Apom Proteins

Cat. No.	Product Name	Accession	Purity
HY-P72297	Apolipoprotein M/APOM Protein, Mouse (P.pastoris, His)	Q9Z1R3 (M1-K190)	≥95%

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00860	APOM Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Apom	NCBI	NCBI:55937

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