BTBD9 Protein, Human (Sf9, His, Strep)

The BTBD9 protein is invovled in regulating hippocampal synaptic plasticity and learning and memory in mice. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster. BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway^[1][2][3]. BTBD9 Protein, Human (Sf9, His, Strep) is the recombinant human-derived BTBD9 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of BTBD9 Protein, Human (Sf9, His, Strep) is 611 a.a., .

The BTBD9 protein contains a BTB/POZ domain and a BACK domain. BTBD9 is widely expressed in the central nervous system of mouse,such as in the thalamus, hypothalamus,etc. Therefore, BTBD9 is invovled in regulating hippocampal synaptic plasticity and learning and memory. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster^[1][2].In additon, BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). Btbd9 knockout mice show motor restlessness, sleep disruption, altered sensory perception and serum iron levels, as well as enhanced fear memory. BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway^[3].

Human

Sf9 insect cells

N-Strep;N-8*His

Q96Q07 (S2-Q612)

114781

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.