C-Reactive Protein, Cynomolgus (HEK293, His)

Reactive protein (CRP) performs multiple functions of host defense, including promoting agglutination, bacterial capsule swelling, phagocytosis, and complement fixation. These activities are promoted by its calcium-dependent binding to phosphocholine, suggesting its role in orchestrating immune responses against pathogens. C-Reactive Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived C-Reactive protein, expressed by HEK293 , with C-His labeled tag. The total length of C-Reactive Protein, Cynomolgus (HEK293, His) is 206 a.a., with molecular weight of 25-30 kDa.

C-Reactive Protein (CRP) plays a multifaceted role in host defense, demonstrating several functions essential for immune responses. CRP promotes agglutination, bacterial capsular swelling, phagocytosis, and complement fixation by binding to phosphorylcholine in a calcium-dependent manner. Additionally, CRP exhibits the ability to interact with DNA and histones, suggesting a potential role in scavenging nuclear material released from damaged circulating cells. These diverse functions underscore CRP's involvement in various aspects of the immune system, contributing to both innate and adaptive immune responses, and highlight its significance as a key player in host defense mechanisms.

Cynomolgus

HEK293

C-His

XP_045255377.1 (Q19-S224)

102126170  [NCBI]

25-30 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.