C-Reactive Protein, Human (HEK293,Tag Free)

C-Reactive Protein, an acute-phase protein, is a marker of inflammation and is produced by the liver. It is used as a diagnostic tool to assess the presence and severity of inflammation in various diseases. C-Reactive Protein's role in inflammation detection and its clinical significance in disease management make it a subject of interest in medical research. C-Reactive Protein, Human (HEK293) is the recombinant human-derived C-Reactive protein, expressed by HEK293 , with tag free.

C-Reactive Protein (CRP) exhibits various functions related to host defense. It facilitates agglutination, bacterial capsular swelling, phagocytosis, and complement fixation by binding to phosphorylcholine in a calcium-dependent manner. CRP is also capable of interacting with DNA and histones, and it may scavenge nuclear material that is released from damaged circulating cells.

Measured by its binding ability in a functional ELISA. When human Fc gamma RIIA（HY-P70711）is immobilized at 2 µg/mL (100 µL/well), can bind Recombinant rhCRP Protein binds with an ED₅₀ of 8.128 μg/mL.

Human

HEK293

Tag Free

P02741-1 (Q19-P224)

1401

QTDMSRKAFVFPKESDTSYVSLKAPLTKPLKAFTVCLHFYTELSSTRGYSIFSYATKRQDNEILIFWSKDIGYSFTVGGSEILFEVPEVTVAPVHICTSWESASGIVEFWVDGKPRVRKSLKKGYTVGAEASIILGQEQDSFGGNFEGSQSLVGDIGNVNMWDFVLSPDEINTIYLGGPFSPNVLNWRALKYEVQGEVFTKPQLWP

Approximately 26 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCL, 150 mM NaCl, 5 mM CaCl2, pH 8.0, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.