Cadherin-17 Protein, Rat (HEK293, His)

Cadherin-17 protein is a calcium-dependent cell adhesion member that plays a crucial role in cell adhesion through self-association. Cadherin-17 Protein, Rat (HEK293, His) is the recombinant rat-derived Cadherin-17 protein, expressed by HEK293 , with C-His labeled tag.

Cadherin-17 is a calcium-dependent cell adhesion protein, belonging to the cadherin family, which is integral for mediating cell-cell adhesion. Exhibiting a preference for homophilic interactions, Cadherin-17 plays a potential role in sorting heterogeneous cell types, contributing to the overall organization of tissues. Specifically, LI-cadherin, may play a role in the morphological organization of the liver and intestine, underlining its significance in maintaining tissue integrity and structure.

Measured by its binding ability in a functional ELISA. Immobilized Rat Cadherin-17, at 2μg/mL (100μL/well) can bind Anti-Cadherin-17 antibody. The ED₅₀ for this effect is 4.017 ng/mL.

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  Measured by its binding ability in a functional ELISA. Immobilized Rat Cadherin-17, at 2μg/mL (100μL/well) can bind Anti- Cadherin-17 antibody. The ED₅₀ for this effect is 4.017 ng/mL.

Rat

HEK293

C-10*His

P55281 (Q22-M786)

117048  [NCBI]

QEGKFSGPLKPMTFSIFEGQEPSQIIFQFKANPPAVTFELTGETDGIFKIEKDGLLYHTRVLDRETRAVHHLQLAALDSQGAIVDGPVPIIIEVKDINDNRPTFLQTKYEGSVRQNSRPGKPFMYVNATDLDDPATPNGQLFYQIVIQLPKINNVMYFQIDNKTGAISLTPEGSQVLDPIKNPYYNLVVSVKDMGGQNENSFSDTTSVDITVRENIWKAPEPVEIRENLTDPHPIKITQVQWNDPGAHYSLINKEKLPQFPFSIDQEGNIYVTQPLDREEKDSHVFFATAKDENGKPLAYPLEIRVKVIDINDNPPTCLSQVTVFEVQENEVLGSSIGIFAAHDMDEANNINSILKYRLVDQTPKVPSDELFLIDEYGGKVQLGKRSLKKQDSPQYNLTVEVSDIDFKTLCSLQVNVIDINDQIPIFERSDYGSKTLSEDTAIGSTILIIQATDDDEPFTGSSKILYKIVQGDTEGRLEVVTDPMTNTGYVKIRKPLDFETEPVTSIVFKAENPEPLVNGIEYNASSFASFELTVTDVNEVPVFPQQIFQANVSEDTAIGTKVGTVTARDPEGLTVSYSLKDNKRGWLKIDSVTGDIFSTAPLDRETESVYRVQVVATEVGGSSLSSTAYFHLVLMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQQSVRRPKFTFALGRESLQSDWEVSKINGTHARLSTKHTRFEEQVYDIPILINDGGQPPMEGIVSLSVTFCQCVDGSCFRPAGNQVGIPTVGM

Approximately 100-130 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.