Cadherin-18 Protein, Rhesus Macaque (HEK293, His)

Cadherin-18, a calcium-dependent cell adhesion protein and member of the cadherin family, regulates cellular adhesion processes. Cadherin-18 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Cadherin-18 protein, expressed by HEK293 , with C-His labeled tag.

Cadherin-18, a member of the cadherin family, belongs to the group of calcium-dependent cell adhesion proteins.

Determined by its ability to inhibit the proliferation of U251 cells. The ED₅₀ for this effect is 29.97 ng/mL, corresponding to a specific activity is 3.34×10⁴ units/mg.

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  Determined by its ability to inhibit the proliferation of U251 cells. The ED₅₀ for this effect is 29.97 ng/mL, corresponding to a specific activity is 3.34×10⁴ units/mg.

Rhesus Macaque

HEK293

C-10*His

F7FMS7/XP_001088306.1 (T25-S608)

701472  [NCBI]

TAHHSSIKVTRNQTKHIEGETEVHHRPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEGANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYVMEVYENAKIGTVVGTVLAQDPDSANSLVRYFINYNAEDDRFFNIDANTGTIKTTKVLDREETPWYNITVTASENDNPDLLSHVTVGIRVLDVNDNPPELAREYDIVVCENSKPGQVIHTISATDKDDFANGPRFNFFLDEHLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSS

Approximately 80-90 kDa due to the glycosylation.

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  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.