Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His)

Cadherin-9 Protein, a calcium-dependent cell adhesion molecule, functions within cellular interactions. Exhibiting calcium-dependent adhesion, CDH9 prefers homophilic interactions, connecting cells. This unique feature suggests a potential role in sorting heterogeneous cell types. The calcium-dependent mechanism underscores cadherins' regulatory role in cellular cohesion within intercellular junctions, maintaining tissue integrity and function. Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is the recombinant cynomolgus-derived Cadherin-3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-3 Protein, Cynomolgus (547a.a, HEK293, His) is 547 a.a., with molecular weight of 70-80 kDa.

Cadherin-9, a calcium-dependent cell adhesion protein, operates as part of the intricate network of cellular interactions. Displaying calcium-dependent adhesion, cadherins like CDH9 exhibit a preference for homophilic interactions, engaging with themselves in connecting cells. This distinctive feature positions cadherins to potentially play a role in the sorting of heterogeneous cell types. The calcium-dependent mechanism underscores the regulatory role of cadherins in cellular cohesion and organization within intercellular junctions, contributing to the overall maintenance of tissue integrity and function.

Anti-CDH3 Antibody captured on CM5 Chip via Protein A can bind Cynomolgus CDH3, His Tag with an affinity constant of 0.37 μM as determined in SPR assay (Biacore T200).

Cynomolgus

HEK293

C-His

XP_005592414.1 (D108-G654)

102142204  [NCBI]

70-80 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from 0.22μm filtered solution in 20mM PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.