1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. K-Cadherin/Cadherin-6
  6. Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His)

Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His)

Cat. No.: HY-P701330
Handling Instructions

Cadherin-6/KCAD Proteinas are calcium-dependent cell adhesion proteins that facilitate cell-to-cell interactions. They preferentially bind to other cadherins of the same type, promoting homophilic interactions. This aids in the organization and sorting of various cell types within tissues. Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is the recombinant human-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is 562 a.a., with molecular weight of 75-95 kDa.

For research use only. We do not sell to patients.

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  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Cadherin-6/KCAD Proteinas are calcium-dependent cell adhesion proteins that facilitate cell-to-cell interactions. They preferentially bind to other cadherins of the same type, promoting homophilic interactions. This aids in the organization and sorting of various cell types within tissues. Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is the recombinant human-derived Cadherin-6/KCAD protein, expressed by HEK293 , with C-His labeled tag. The total length of Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) is 562 a.a., with molecular weight of 75-95 kDa.

Background

Cadherins are a group of calcium-dependent cell adhesion proteins that play a crucial role in cell-to-cell interactions. They have a preference for binding to other cadherins of the same type, known as homophilic interactions, which helps in the organization and sorting of different cell types within tissues.

Biological Activity

Immobilized Human CDH6, His Tag at 2 μg/mL (100 μl/well) on the plate. Dose response curve for Anti-CDH6 Antibody, Rabbit IgG Tag with the EC50 of 76.8 ng/mL determined by ELISA.

Species

Human

Source

HEK293

Tag

C-His

Accession

P55285-1 (S54-A615)

Gene ID

1004

Molecular Construction
N-term
CDH6 (S54-A615)
Accession # P55285-1
His
C-term
Synonyms
Cadherin-6; Cadherin6; K-cadherin; CDH6; CAD6; KCAD;
AA Sequence

SWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKVEASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGA

Molecular Weight

75-95 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Cadherin-6/KCAD Protein, Human (562a.a, HEK293, His)
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HY-P701330
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