2. Recombinant Proteins
  3. Cytokines and Growth Factors CAR-T Related Proteins CD Antigens
  4. TNF Superfamily T Cell CD Proteins Macrophage CD Proteins Erythrocyte CD Proteins
  5. TNF Receptor Superfamily CD30
  6. CD30/TNFRSF8 Protein, Human (HEK293, hFc)

CD30/TNFRSF8 Protein, Human (HEK293, hFc)

Cat. No.: HY-P75421
Handling Instructions

CD30/TNFRSF8 protein (TNFSF8/CD30L receptor) is a key factor regulating cell growth and lymphoblast transformation and may activate NF-kappa-B signaling. CD30/TNFRSF8 Protein, Human (HEK293, hFc) is the recombinant human-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD30/TNFRSF8 Protein, Human (HEK293, hFc) is 361 a.a., with molecular weight of ~65.2 kDa.

For research use only. We do not sell to patients.

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Description

CD30/TNFRSF8 protein (TNFSF8/CD30L receptor) is a key factor regulating cell growth and lymphoblast transformation and may activate NF-kappa-B signaling. CD30/TNFRSF8 Protein, Human (HEK293, hFc) is the recombinant human-derived CD30/TNFRSF8 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD30/TNFRSF8 Protein, Human (HEK293, hFc) is 361 a.a., with molecular weight of ~65.2 kDa.
Background

CD30/TNFRSF8 protein, as a receptor for TNFSF8/CD30L, plays a key role in the regulation of cell growth and transformation of activated lymphoblasts. In addition, it may participate in the regulation of gene expression through the activation of NF-kappa-B signaling, thereby promoting a variety of cellular processes.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

P28908 (F19-K379)
Gene ID

943  [NCBI]
Molecular Construction
N-term
CD30 (F19-K379)
Accession # P28908
hFc
C-term
Synonyms
CD30L receptor; Tumor necrosis factor receptor superfamily member 8; Ki-1 antigen
Molecular Weight

Approximately 65.2 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CD30/TNFRSF8 Protein, Human (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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