CD6 Protein, Human (HEK293, His)

The CD6 protein is located on the outer membrane of T lymphocytes and other immune cells. It has three cysteine-rich scavenger receptor (SRCR) domains and a binding site for activated leukocyte cell adhesion molecules. CD6 Protein, Human (HEK293, His) is the recombinant human-derived CD6 protein, expressed by HEK293 , with C-His labeled tag. The total length of CD6 Protein, Human (HEK293, His) is 385 a.a., with molecular weight of 70-90 kDa.

The CD6 protein is situated on the outer membrane of T-lymphocytes and various other immune cells. Featuring three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule, this protein plays a crucial role in sustaining T cell activation. Additionally, there is evidence suggesting an association between this gene and susceptibility to multiple sclerosis. Multiple transcript variants, encoding diverse isoforms, have been identified for this gene, with biased expression observed in lymph node, appendix, and nine other tissues.

Human

HEK293

C-His

NP_006716.3 (H18-L402)

923  [NCBI]

70-90 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.