1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Peptide Hormone & Neuropeptides
  4. Choriogonadotropin Subunit beta 7 (CGB7)
  5. CGB7 Protein, Human (sf9, His)

CGB7 Protein, Human (sf9, His)

Cat. No.: HY-P76820
Handling Instructions

The CGB7 protein is the beta subunit of human chorionic gonadotropin (hCG) and is critical during pregnancy, stimulating steroid synthesis that is essential for maintaining pregnancy. As a unique β subunit, CGB7 confers hCG specificity and plays a unique role in reproductive physiology. CGB7 Protein, Human (sf9, His) is the recombinant human-derived CGB7 protein, expressed by Sf9 insect cells , with C-His labeled tag.

For research use only. We do not sell to patients.

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Description

The CGB7 protein is the beta subunit of human chorionic gonadotropin (hCG) and is critical during pregnancy, stimulating steroid synthesis that is essential for maintaining pregnancy. As a unique β subunit, CGB7 confers hCG specificity and plays a unique role in reproductive physiology. CGB7 Protein, Human (sf9, His) is the recombinant human-derived CGB7 protein, expressed by Sf9 insect cells , with C-His labeled tag.

Background

The CGB7 Protein serves as the beta subunit of human chorionic gonadotropin (hCG), a complex glycoprotein composed of two glycosylated subunits, alpha and beta, which are non-covalently associated. The alpha subunit is identical to those found in pituitary gonadotropin hormones (LH, FSH, and TSH). Notably, the beta subunits are distinct in each of the hormones, conferring receptor and biological specificity. CGB7 plays an essential role in pregnancy and maternal adaptation, stimulating the ovaries to synthesize steroids crucial for maintaining pregnancy. It functions as a heterodimer, consisting of a common alpha chain identical in LH, FSH, TSH, and HCG, and a unique beta chain that imparts specificity to each hormone. Understanding the role of CGB7 contributes to our knowledge of reproductive physiology, with potential implications for fertility treatments and maternal health. Further exploration of CGB7's functions holds promise for enhancing our understanding of its contributions to the intricate processes of pregnancy and reproductive adaptation.

Species

Human

Source

Sf9 insect cells

Tag

C-His

Accession

P0DN87-1 (S21-Q165)

Gene ID
Molecular Construction
N-term
CGB7 (S21-Q165)
Accession # P0DN87-1
His
C-term
Synonyms
Choriogonadotropin subunit beta 7; CGB7
Molecular Weight

Approximately 25 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CGB7 Protein, Human (sf9, His)
Cat. No.:
HY-P76820
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