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  4. CHI3L2 Protein, Human (HEK293, His)

CHI3L2 Protein, Human (HEK293, His)

Cat. No.: HY-P7816
Handling Instructions

CHI3L2, a lectin, exhibits high affinity for chitooligosaccharides and diverse glycans, except heparin. Importantly, CHI3L2 lacks chitinase activity, setting it apart from enzymes involved in chitin hydrolysis. CHI3L2 Protein, Human (HEK293, His) is the recombinant human-derived CHI3L2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CHI3L2 Protein, Human (HEK293, His) is 364 a.a., with molecular weight of ~40.0 kDa.

For research use only. We do not sell to patients.

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Description

CHI3L2, a lectin, exhibits high affinity for chitooligosaccharides and diverse glycans, except heparin. Importantly, CHI3L2 lacks chitinase activity, setting it apart from enzymes involved in chitin hydrolysis. CHI3L2 Protein, Human (HEK293, His) is the recombinant human-derived CHI3L2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of CHI3L2 Protein, Human (HEK293, His) is 364 a.a., with molecular weight of ~40.0 kDa.
Background

The CHI3L2 protein functions as a lectin, displaying a high affinity for chitooligosaccharides and various glycans, excluding heparin. Notably, CHI3L2 lacks chitinase activity, distinguishing it from enzymes that typically catalyze the hydrolysis of chitin.
Species

Human
Source

HEK293
Tag

C-6*His
Accession

AAH11460.1 (Y27-L390)
Gene ID
Molecular Construction
N-term
CHI3L2 (Y27-L390)
Accession # AAH11460.1
6*His
C-term
Synonyms
rHuChitinase-3-like protein 2/CHI3L2, His; Chitinase-3-Like Protein 2; Chondrocyte Protein 39; YKL-39; CHI3L2
AA Sequence

YKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL

Molecular Weight

Approximately 40.0 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

CHI3L2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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