CK1γ3 Protein, Human (Sf9, GST)

The CK1γ3 protein is a serine/threonine protein kinase in the casein kinase family that prefers acidic proteins, including casein. It has broad substrate specificity and can phosphorylate a variety of proteins, affecting diverse cellular processes. CK1γ3 Protein, Human (Sf9, GST) is the recombinant human-derived CK1γ3 protein, expressed by Sf9 insect cells , with N-GST labeled tag.

CK1γ3, a serine/threonine-protein kinase within the casein kinase family, is characterized by its distinctive preference for acidic proteins, with caseins among its favored substrates. This kinase exhibits broad substrate specificity, phosphorylating numerous proteins to influence diverse cellular processes. Notably, CK1γ3 actively participates in the intricate Wnt signaling pathway, contributing to the modulation of cellular responses. Additionally, it plays a regulatory role in fast synaptic transmission mediated by glutamate, indicating its involvement in synaptic processes and neurotransmitter signaling, as suggested by functional similarities with other members of the casein kinase family.

Human

Sf9 insect cells

N-GST

Q9Y6M4 (E2-K447)

1456

Greater than 75% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.