1. Recombinant Proteins
  2. Others
  3. Claudin-11/CLDN11 Protein, Human (HEK293, Fc)

Claudin-11/CLDN11 Protein, Human (HEK293, Fc)

Cat. No.: HY-P74250
Handling Instructions

Claudin-11/CLDN11 Protein plays a crucial role in tightly closing intercellular spaces in tight junctions, facilitated by its calcium-independent cell-adhesion capabilities. Interacting with tetraspanin-3/TSPAN3 suggests potential collaboration in cellular processes. CLDN11's associations with OCLN highlight its involvement in molecular interactions, contributing to the structural integrity and functional regulation of tight junctions. Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is the recombinant human-derived Claudin-11/CLDN11 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is 60 a.a., with molecular weight of ~37 kDa.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

Claudin-11/CLDN11 Protein plays a crucial role in tightly closing intercellular spaces in tight junctions, facilitated by its calcium-independent cell-adhesion capabilities. Interacting with tetraspanin-3/TSPAN3 suggests potential collaboration in cellular processes. CLDN11's associations with OCLN highlight its involvement in molecular interactions, contributing to the structural integrity and functional regulation of tight junctions. Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is the recombinant human-derived Claudin-11/CLDN11 protein, expressed by HEK293 , with N-mFc labeled tag. The total length of Claudin-11/CLDN11 Protein, Human (HEK293, Fc) is 60 a.a., with molecular weight of ~37 kDa.

Background

Claudin-11 (CLDN11) assumes a crucial role in the precise closure of the intercellular space within tight junctions, primarily facilitated by its calcium-independent cell-adhesion capabilities. This protein also engages in interactions with tetraspanin-3/TSPAN3, indicating potential collaborative roles within cellular processes. Furthermore, CLDN11 forms associations with OCLN, as observed in experimental findings, elucidating its involvement in molecular interactions that contribute to the structural integrity and functional regulation of tight junctions.

Species

Human

Source

HEK293

Tag

N-mFc

Accession

O75508 (V23-R82)

Gene ID
Molecular Construction
N-term
mFc
CLDN11 (V23-R82)
Accession # O75508
C-term
Synonyms
Claudin-11; CLDN11; OSP; OTM
Molecular Weight

Approximately 37 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Claudin-11/CLDN11 Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Claudin-11/CLDN11 Protein, Human (HEK293, Fc)
Cat. No.:
HY-P74250
Quantity:
MCE Japan Authorized Agent: