1. Recombinant Proteins
  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. C-Type Lectin Domain Family 10 Member A/CD301
  6. CLEC10A/CD301 Protein, Mouse (HEK293, Fc)

CLEC10A/CD301 Protein, Mouse (HEK293, Fc)

Cat. No.: HY-P76265
COA Handling Instructions

CLEC10A/CD301 has predicted carbohydrate-binding activity and plays an upstream role in connective tissue replacement in inflammatory responses and wound healing. This protein is expected to be located on the membrane and be an integral part of the membrane structure, being active on the outside of the plasma membrane. CLEC10A/CD301 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.

For research use only. We do not sell to patients.

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5 μg $63 In-stock
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Description

CLEC10A/CD301 has predicted carbohydrate-binding activity and plays an upstream role in connective tissue replacement in inflammatory responses and wound healing. This protein is expected to be located on the membrane and be an integral part of the membrane structure, being active on the outside of the plasma membrane. CLEC10A/CD301 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CLEC10A/CD301 protein, expressed by HEK293 , with N-hFc labeled tag.

Background

CLEC10A/CD301, a protein with predicted carbohydrate binding activity, plays a role upstream of connective tissue replacement involved in inflammatory response and wound healing. Anticipated to be located in the membrane and serve as an integral component of membrane structure, this protein is predicted to be active on the external side of the plasma membrane. Expression of CLEC10A is detected in various structures, including cartilage, dermis, embryo mesenchyme, metencephalon part of the 4th ventricle choroid plexus, and spinal cord marginal layer. The biased expression of CLEC10A in tissues such as mammary gland (RPKM 20.4) and bladder (RPKM 15.0) suggests its potential involvement in diverse physiological processes across different tissues.

Species

Mouse

Source

HEK293

Tag

N-hFc

Accession

NP_001191181.1 (Q58-S305)

Gene ID
Molecular Construction
N-term
hFc
CLEC10A/CD301 (Q58-S305)
Accession # NP_001191181.1
C-term
Synonyms
C-type lectin domain family 10 member A; CD301; CLEC10A; CLECSF13; CLECSF14; HML
AA Sequence

QNSQLRRDLGTLRATLDNTTSKIKAEFQSLDSRADSFEKGISSLKVDVEDHRQELQAGRDLSQKVTSLESTVEKREQALKTDLSDLTDHVQQLRKDLKALTCQLANLKNNGSEVACCPLHWTEHEGSCYWFSESEKSWPEADKYCRLENSHLVVVNSLEEQNFLQNRLANVVSWIGLTDQNGPWRWVDGTDFEKGFKNWAPLQPDNWFGHGLGGGEDCAHITTGGPWNDDVCQRTFRWICEMKLAKES

Molecular Weight

Approximately 58 kDa.

Purity
  • Greater than 95% as determined by reducing SDS-PAGE.
Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CLEC10A/CD301 Protein, Mouse (HEK293, Fc)
Cat. No.:
HY-P76265
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