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  2. Receptor Proteins
  3. Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. CLL-1
  6. CLEC12A/MICL Protein, Mouse (HEK293, His)

CLEC12A/MICL Protein, Mouse (HEK293, His)

Cat. No.: HY-P77905
COA Handling Instructions

CLEC12A/MICL protein acts as a cell surface receptor, facilitating tyrosine phosphorylation of MAP kinases and modulating signaling cascades. It interacts with PTPN6 and PTPN11, key proteins in signaling pathways. CLEC12A/MICL Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag. The total length of CLEC12A/MICL Protein, Mouse (HEK293, His) is 203 a.a., with molecular weight of 30-40 kDa.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
20 μg $130 In-stock
50 μg $280 In-stock
100 μg   Get quote  

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  • Biological Activity

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Description

CLEC12A/MICL protein acts as a cell surface receptor, facilitating tyrosine phosphorylation of MAP kinases and modulating signaling cascades. It interacts with PTPN6 and PTPN11, key proteins in signaling pathways. CLEC12A/MICL Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag. The total length of CLEC12A/MICL Protein, Mouse (HEK293, His) is 203 a.a., with molecular weight of 30-40 kDa.

Background

CLEC12A/MICL protein is a cell surface receptor that plays a crucial role in modulating signaling cascades and facilitating the tyrosine phosphorylation of target MAP kinases. It interacts with PTPN6 and PTPN11, two important proteins involved in signaling pathways.

Species

Mouse

Source

HEK293

Tag

N-His

Accession

Q504P2 (Y65-R267)

Gene ID
Molecular Construction
N-term
His
CLEC12A (Y65-R267)
Accession # Q504P2
C-term
Synonyms
MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
Molecular Weight

30-40 kDa

Purity

Greater than 95% as determined by Tris-Bis PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

CLEC12A/MICL Protein, Mouse (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
CLEC12A/MICL Protein, Mouse (HEK293, His)
Cat. No.:
HY-P77905
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