1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Immunoglobulin-like Cell Adhesion Molecules
  5. Contactin-3
  6. Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc)

Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc)

Cat. No.: HY-P72947
SDS COA Handling Instructions

Contactin-3/CNTN3 protein, a member of the contactin family, facilitates cell surface interactions crucial for nervous system development. It exhibits neurite outgrowth-promoting activity, contributing to the intricate processes involved in the formation and maturation of neural circuits. Additionally, Contactin-3/CNTN3 interacts with PTPRG, indicating its involvement in signaling pathways that govern neural cell communication and connectivity. Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc) is the recombinant human-derived Contactin-3/CNTN3 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Description

Contactin-3/CNTN3 protein, a member of the contactin family, facilitates cell surface interactions crucial for nervous system development. It exhibits neurite outgrowth-promoting activity, contributing to the intricate processes involved in the formation and maturation of neural circuits. Additionally, Contactin-3/CNTN3 interacts with PTPRG, indicating its involvement in signaling pathways that govern neural cell communication and connectivity. Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc) is the recombinant human-derived Contactin-3/CNTN3 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Contactin-3 (CNTN3) is a protein that plays a crucial role in mediating cell surface interactions during nervous system development. Functionally, it exhibits neurite outgrowth-promoting activity, suggesting its involvement in promoting the extension of neuronal processes (By similarity). Additionally, CNTN3 interacts with PTPRG, indicating a potential role in modulating signaling pathways or cellular adhesion during neural development. The complex interplay between Contactin-3 and its interacting partners underscores its significance in the intricate processes of nervous system development, where cell surface interactions and neurite outgrowth are essential for the establishment of functional neural circuits.

Species

Human

Source

HEK293

Tag

C-hFc

Accession

Q9P232/NP_065923.1 (E20-S1002, N708D)

Gene ID
Molecular Construction
N-term
CNTN3 (E20-S1002, N708D)
Accession # Q9P232/NP_065923.1
hFc
C-term
Synonyms
Contactin-3; BIG-1; CNTN3; KIAA1496; PANG
AA Sequence

MMFPWKQLILLSFIGCLGGELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVDGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGS

Molecular Weight

160-170 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE

Appearance

Solution

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Contactin-3/CNTN3 Protein, Human (N708D, HEK293, Fc)
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HY-P72947
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