CSPG5 Protein, Mouse (HEK293, His)

CSPG5 protein plays a key role as a growth and differentiation factor in neuritogenesis and may induce ERBB3 activation and participate in signaling pathways related to cell growth and differentiation. Its ability to bind to TNR and possibly TNC suggests interactions with key molecules in cellular processes. CSPG5 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CSPG5 protein, expressed by HEK293 , with C-His labeled tag.

The CSPG5 protein appears to play a pivotal role as a growth and differentiation factor in neuritogenesis. Its potential induction of ERBB3 activation underscores its involvement in signaling pathways associated with cellular growth and differentiation. CSPG5 also exhibits binding capabilities with TNR and likely TNC, suggesting its interaction with key molecules in cellular processes. Furthermore, it interacts with ERBB3 and GOPC, indicating a network of associations that may contribute to its functional roles. Notably, CSPG5 interacts with MDK independently of the presence of chondroitin sulfate chains, promoting the elongation of oligodendroglial precursor-like cells. These findings highlight the multifaceted nature of CSPG5's involvement in neurodevelopmental processes, suggesting its significance in orchestrating cellular responses and interactions critical for proper nervous system development.

Mouse

HEK293

C-His

Q71M36-1 (V31-C423)

29873  [NCBI]

60-80 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder

Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.