2. Recombinant Proteins
  3. CD Antigens Receptor Proteins
  4. Endothelial cell CD Proteins Cell Adhesion Molecules (CAMs)
  5. E-Selectin/CD62E Selectin
  6. E-Selectin/CD62E
  7. E-Selectin/CD62E Protein, Human (HEK293, His-Avi)

E-Selectin/CD62E Protein, Human (HEK293, His-Avi)

Cat. No.: HY-P78437
Handling Instructions Technical Support

E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is 535 a.a., with molecular weight of 80-100 kDa.

For research use only. We do not sell to patients.

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Description

E-selectin/CD62E Protein, a cell-surface glycoprotein, crucially mediates immunoadhesion by interacting with SELPLG/PSGL1 for the adhesion of neutrophils to cytokine-activated endothelium. It also potentially influences capillary morphogenesis and interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, independently of SELPLG sulfation. E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is the recombinant human-derived E-Selectin/CD62E protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of E-Selectin/CD62E Protein, Human (HEK293, His-Avi) is 535 a.a., with molecular weight of 80-100 kDa.
Background

E-selectin/CD62E Protein is a cell-surface glycoprotein that plays a crucial role in immunoadhesion. It mediates the adhesion of blood neutrophils in cytokine-activated endothelium by interacting with SELPLG/PSGL1. Additionally, E-selectin/CD62E Protein may be involved in capillary morphogenesis. It interacts with SELPLG/PSGL1 and PODXL2 through the sialyl Lewis X epitope, and it is worth noting that SELPLG sulfation is not necessary for this interaction.
Species

Human
Source

HEK293
Tag

C-Avi;C-His
Accession

P16581 (W22-P556)
Gene ID
Molecular Construction
N-term
CD62E (W22-P556)
Accession # P16581
His-Avi
C-term
Synonyms
CD62E; ELAM; ELAM1; ESEL; E-Selectin; LECAM2; SELE; selectin E; RP1-117P20.2
Molecular Weight

80-100 kDa
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

E-Selectin/CD62E Protein, Human (HEK293, His-Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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