EPCR Protein, Human (HEK293, His)

EPCR Protein binds activated protein C, enhancing its activation by the thrombin-thrombomodulin complex, and is pivotal in the protein C pathway, regulating blood coagulation. EPCR Protein, Human (HEK293, His) is the recombinant human-derived EPCR protein, expressed by HEK293 , with C-6*His labeled tag. The total length of EPCR Protein, Human (HEK293, His) is 193 a.a., with molecular weight of ~37.0 kDa.

EPCR protein is capable of binding activated protein C and acts to enhance its activation by the thrombin-thrombomodulin complex. This protein plays a crucial role in the protein C pathway, which regulates blood coagulation.

Human

HEK293

C-6*His

Q9UNN8 (S18-S210)

10544  [NCBI]

SQDASDGLQRLHMLQISYFRDPYHVWYQGNASLGGHLTHVLEGPDTNTTIIQLQPLQEPESWARTQSGLQSYLLQFHGLVRLVHQERTLAFPLTIRCFLGCELPPEGSRAHVFFEVAVNGSSFVSFRPERALWQADTQVTSGVVTFTLQQLNAYNRTRYELREFLEDTCVQYVQKHISAENTKGSQTSRSYTS

Approximately 37.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.