2. Recombinant Proteins
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Eph Receptors
  6. EphA1
  7. EphA1 Protein, Human (sf9, His, GST)

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (sf9, His, GST) is the recombinant human-derived EphA1, expressed by Sf9 insect cells , with His, GST labeled tag. The total length of EphA1 Protein, Human (sf9, His, GST) is 409 a.a.,

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Description

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (sf9, His, GST) is the recombinant human-derived EphA1, expressed by Sf9 insect cells , with His, GST labeled tag. The total length of EphA1 Protein, Human (sf9, His, GST) is 409 a.a.,
Background

EphA1 protein is a receptor tyrosine kinase that interacts with membrane-bound ephrin-A ligands on neighboring cells, resulting in contact-dependent bidirectional signaling. This receptor mediates both forward signaling and reverse signaling pathways. Activation by its high-affinity ligand EFNA1 regulates various cellular processes, including cell attachment, motility, angiogenesis, and proliferation. Additionally, EphA1 may play a role in apoptosis.
Species

Human
Source

Sf9 insect cells
Tag

His;GST
Accession

P21709-1 (F568-D976)
Gene ID

2041
Synonyms
EPHA1; Eph receptor A1; ephrin type-A receptor 1; mEpha1; embryonic stem cell kinase; tyrosine-protein kinase receptor ESK; Eph; Esk; AL033318; 5730453L17Rik
Purity

Greater than 80 % as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

EphA1 Protein, Human (sf9, His, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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