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  2. Cytokines and Growth Factors
  3. Ephrin/Eph Family
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  5. Ephrin B2
  6. Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc)

Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc)

Cat. No.: HY-P75231
Handling Instructions

Ephrin-B2/EFNB2 Protein, a member of the ephrin family, serves as a transmembrane ligand, interacting with its Eph receptor to initiate bidirectional signaling. Crucial in developmental processes like tissue boundary formation, axon guidance, angiogenesis, and synaptic plasticity, Ephrin-B2/EFNB2 is implicated in conditions like cancer, cardiovascular diseases, and neurological disorders, making it a potential therapeutic target. Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc) is the recombinant canine-derived Ephrin-B2/EFNB2 protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Description

Ephrin-B2/EFNB2 Protein, a member of the ephrin family, serves as a transmembrane ligand, interacting with its Eph receptor to initiate bidirectional signaling. Crucial in developmental processes like tissue boundary formation, axon guidance, angiogenesis, and synaptic plasticity, Ephrin-B2/EFNB2 is implicated in conditions like cancer, cardiovascular diseases, and neurological disorders, making it a potential therapeutic target. Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc) is the recombinant canine-derived Ephrin-B2/EFNB2 protein, expressed by HEK293 , with C-hFc labeled tag.

Background

Ephrin-B2/EFNB2 protein is a member of the ephrin family, a group of proteins that play important roles in cellular signaling and communication. Ephrin-B2/EFNB2 specifically functions as a transmembrane ligand, interacting with its corresponding Eph receptor to initiate bidirectional signaling events that regulate diverse cellular processes. This protein is involved in various developmental processes, including tissue boundary formation, axon guidance, angiogenesis, and synaptic plasticity. Additionally, Ephrin-B2/EFNB2 has been implicated in pathological conditions such as cancer, cardiovascular diseases, and neurological disorders, making it a potential therapeutic target for intervention.

Species

Canine

Source

HEK293

Tag

C-hFc

Accession

B0LDS6 (I28-A229)

Gene ID
Molecular Construction
N-term
EFNB2 (I28-A229)
Accession # B0LDS6
hFc
C-term
Synonyms
Ephrin-B2; LERK-5; HTK-L; EFNB2; EPLG5
Molecular Weight

Approximately 58&35 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Ephrin-B2/EFNB2 Protein, Canine (HEK293, hFc)
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HY-P75231
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