FGF-18 Protein, Mouse (HEK293, His)

The FGF-18 protein plays a key role in regulating cell proliferation, differentiation, and migration, particularly in normal ossification and bone development, showing its critical role in skeletal maturation. In addition, FGF-18 stimulates liver and intestinal proliferation, highlighting its multifunctional role in various tissues. FGF-18 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGF-18 protein, expressed by HEK293 , with C-His labeled tag.

FGF-18 protein assumes a pivotal role in orchestrating the intricate regulation of cell proliferation, differentiation, and migration. Its indispensable functions extend to the realm of normal ossification and bone development, highlighting its critical involvement in skeletal maturation. Furthermore, FGF-18 exhibits the capacity to stimulate hepatic and intestinal proliferation, underscoring its versatile role in various tissues. The orchestration of these cellular processes is facilitated through interactions with FGFR3 and FGFR4, underscoring the significance of FGF-18 in mediating intricate signaling pathways that contribute to the fundamental processes of tissue development and homeostasis.

Mouse

HEK293

C-His

O89101 (E28-G207)

14172  [NCBI]

30-35 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.