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  3. FLT3LG Protein, Human (Tag Free)

FLT3LG Protein, Human (Tag Free)

Cat. No.: HY-P700072
Handling Instructions

FLT3LG Proteinas, a potent stimulator of early hematopoietic cell proliferation, activates FLT3 and synergizes with colony-stimulating factors and interleukins. As a homodimer, especially in isoform 2, it crucially promotes expansion and differentiation of hematopoietic progenitor cells. FLT3LG's collaborative signaling with other molecules underscores its significance in regulating hematopoiesis and maintaining hematopoietic system balance. FLT3LG Protein, Human (Tag Free) is the recombinant human-derived FLT3LG protein, expressed by E. coli, with tag free. The total length of FLT3LG Protein, Human (Tag Free) is 155 a.a., with molecular weight of ~17.61 kDa.

For research use only. We do not sell to patients.

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Description

FLT3LG Proteinas, a potent stimulator of early hematopoietic cell proliferation, activates FLT3 and synergizes with colony-stimulating factors and interleukins. As a homodimer, especially in isoform 2, it crucially promotes expansion and differentiation of hematopoietic progenitor cells. FLT3LG's collaborative signaling with other molecules underscores its significance in regulating hematopoiesis and maintaining hematopoietic system balance. FLT3LG Protein, Human (Tag Free) is the recombinant human-derived FLT3LG protein, expressed by E. coli, with tag free. The total length of FLT3LG Protein, Human (Tag Free) is 155 a.a., with molecular weight of ~17.61 kDa.

Background

FLT3LG protein serves as a potent stimulator of early hematopoietic cell proliferation through the activation of FLT3, demonstrating synergistic effects when combined with various colony-stimulating factors and interleukins. This homodimeric protein, particularly in isoform 2, plays a crucial role in promoting the expansion and differentiation of hematopoietic progenitor cells. Its ability to activate FLT3 and collaborate with other signaling molecules underscores its significance in regulating hematopoiesis and maintaining the balance of the hematopoietic system.

Species

Human

Source

E. coli

Tag

Tag Free

Accession

P49771-1 (T27-A181)

Gene ID

2323

Molecular Construction
N-term
FLT3LG (T27-A181)
Accession # P49771-1
C-term
Synonyms
Flt-3 Ligand; Flt3 ligand; FL; SL cytokine; Flt-3L
AA Sequence

TQDCSFQHSPISSDFAVKIRELSDYLLQDYPVTVASNLQDEELCGGLWRLVLAQRWMERLKTVAGSKMQGLLERVNTEIHFVTKCAFQPPPSCLRFVQTNISRLLQETSEQLVALKPWITRQNFSRCLELQCQPDSSTLPPPWSPRPLEATAPTA

Molecular Weight

Approximately 17.61 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Endotoxin Level

< 1 EU/μg of protein by gel clotting method

Documentation

FLT3LG Protein, Human (Tag Free) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FLT3LG Protein, Human (Tag Free)
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HY-P700072
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