FNTA Protein, Human (His, Strep)

FNTA protein is a key subunit in the farnesyltransferase and geranylgeranyltransferase complexes, which can transfer farnesyl or geranylgeranyl moieties to proteins with Cys-aliphatic-aliphatic-X sequence cysteine residues in proteins. This enzymatic activity contributes to post-translational protein modifications. FNTA Protein, Human (His, Strep) is the recombinant human-derived FNTA protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of FNTA Protein, Human (His, Strep) is 379 a.a., .

FNTA Protein serves as an essential subunit in both the farnesyltransferase and geranylgeranyltransferase complexes, playing a crucial role in transferring farnesyl or geranylgeranyl moieties to cysteine residues within proteins characterized by the C-terminal sequence Cys-aliphatic-aliphatic-X. This enzymatic activity contributes to the post-translational modification of various proteins. Moreover, FNTA may play a positive regulatory role in neuromuscular junction development, acting downstream of MUSK by facilitating the prenylation and activation of RAC1. This highlights the protein's involvement in cellular processes with broader implications for signaling and cellular structure.

Human

E. coli

N-Strep;N-6*His

P49354 (M1-Q379)

2339

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.