Fructose-bisphosphate aldolase A/ALDOA Protein, Human (364aa, His)

Fructose-bisphosphate aldolase A (ALDOA) is a key enzyme that catalyzes the reversible conversion of β-D-fructose 1,6-bisphosphate (FBP) into two triose phosphates in glycolysis and gluconeogenesis. play a central role. By mediating this critical step in carbohydrate metabolism, ALDOA helps produce energy and metabolic intermediates necessary for cellular function. Fructose-bisphosphate aldolase A/ALDOA Protein, Human (364aa, His) is the recombinant human-derived Fructose-bisphosphate aldolase A/ALDOA protein, expressed by E. coli , with N-6*His labeled tag. The total length of Fructose-bisphosphate aldolase A/ALDOA Protein, Human (364aa, His) is 363 a.a., with molecular weight of 45.3 kDa.

Fructose-bisphosphate aldolase A (ALDOA) is a pivotal enzyme that catalyzes the reversible conversion of beta-D-fructose 1,6-bisphosphate (FBP) into two triose phosphates, playing a crucial role in both glycolysis and gluconeogenesis. This enzymatic activity is integral to the breakdown of glucose for energy production and the synthesis of glucose from non-carbohydrate precursors. Beyond its role in carbohydrate metabolism, ALDOA may also function as a scaffolding protein, suggesting additional roles in cellular processes beyond its classical enzymatic function. The versatility of ALDOA in glycolytic and non-glycolytic functions highlights its importance in various cellular processes and underscores its potential significance as a therapeutic target.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

E. coli

N-6*His

P04075 (P2-Y364)

226  [NCBI]

MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY

45.3 kDa

Greater than 90% as determined by SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.