2. Recombinant Proteins
  3. Cytokines and Growth Factors Biotinylated Proteins
  4. TGF-beta Superfamily Neurotrophic Factors
  5. TGF-β TGF-β
  6. TGF-β1
  7. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi)

GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi)

Cat. No.: HY-P700864
Handling Instructions

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

Size Stock
50 μg   Get quote  
100 μg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

  • Biological Activity

  • Technical Parameters

  • Properties

  • Documentation

Description

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing rat-derived GARP&Latent TGF Beta 1 Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of 70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L, respectively.
Background

GARP is a transmembrane protein that acts as a docking receptor for potential transforming growth factor (LTGF-β) and plays a key role in the production and release of active transforming growth factor β (TGF-β). The presence of GARP as a soluble factor and surface marker for different cell types affects immune-mediated diseases such as cancer, allergies, and autoimmunity. GARP can be used as a biomarker and therapeutic target[1][2].
Species

Rat
Source

HEK293
Tag

C-Avi;C-His
Accession

D3ZVD5 (I18-N628)&P17246 (L30-R278)
Gene ID

293135&59086
Synonyms
LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1; TGF-β-1; LRRC32&TGF-β 1; GARP&Latent TGF Beta; GARP&Latent TGF Beta 1
Molecular Weight

70-80 kDa (GARP) & 42-48 kDa & 13 kDa (L
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
GARP&Latent TGF Beta 1 Complex Protein, Human (Biotinylated, HEK293, His-Avi)
Cat. No.:
HY-P700864
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.