GLUD1 Protein, Human

GLUD1 protein is a mitochondrial glutamate dehydrogenase that converts L-glutamate into α-ketoglutarate, supporting glutamine anaplerosis and the tricarboxylic acid cycle. In addition to metabolism, GLUD1 plays a key role in insulin homeostasis, complexly regulating glucose metabolism. GLUD1 Protein, Human is the recombinant human-derived GLUD1 protein, expressed by E. coli , with tag free. The total length of GLUD1 Protein, Human is 505 a.a., .

GLUD1 protein, a mitochondrial glutamate dehydrogenase, stands as a critical catalyst in the conversion of L-glutamate to alpha-ketoglutarate, thereby playing a pivotal role in glutamine anaplerosis and supplying the tricarboxylic acid cycle with a crucial intermediate. Beyond its metabolic functions, GLUD1 emerges as a key player in insulin homeostasis, contributing to the intricate regulation of glucose metabolism. Additionally, there is suggestive evidence implicating GLUD1 in cognitive processes, hinting at its potential involvement in learning and memory reactions through modulation of the excitatory neurotransmitter glutamate turnover.

Human

E. coli

Tag Free

P00367 (S54-T558)

2746

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.