GPD1 Protein, Human (HEK293, His)

GPD1 protein, a glycerol-3-phosphate dehydrogenase, crucially converts glycerol-3-phosphate to dihydroxyacetone phosphate, a key step in glycolysis and gluconeogenesis. Its enzymatic activity regulates cellular energy metabolism and glycerolipid biosynthesis, essential for maintaining cellular homeostasis and energy production. GPD1's role makes it a key player in metabolic processes with implications for various physiological functions. GPD1 Protein, Human (HEK293, His) is the recombinant human-derived GPD1 protein, expressed by HEK293 , with C-6*His labeled tag.

GPD1 protein serves as a glycerol-3-phosphate dehydrogenase, playing a crucial role in the metabolic conversion of glycerol-3-phosphate. This enzymatic activity involves the oxidation of glycerol-3-phosphate to dihydroxyacetone phosphate, a key step in glycolysis and gluconeogenesis pathways. By catalyzing this reaction, GPD1 contributes to the regulation of cellular energy metabolism and the balance of glycerolipid biosynthesis. The glycerol-3-phosphate dehydrogenase activity of GPD1 is essential for maintaining cellular homeostasis and energy production, making it a key player in metabolic processes with implications for various physiological functions.

Measured by its ability to catalyze dihydroxyacetone phosphate (DHAP) to glycerol-3-phosphate. The specific activity is 524.773-557.050 pmol/min/ug.

Human

HEK293

C-6*His

P21695-1 (M1-M349)

2819  [NCBI]

MASKKVCIVGSGNWGSAIAKIVGGNAAQLAQFDPRVTMWVFEEDIGGKKLTEIINTQHENVKYLPGHKLPPNVVAVPDVVQAAEDADILIFVVPHQFIGKICDQLKGHLKANATGISLIKGVDEGPNGLKLISEVIGERLGIPMSVLMGANIASEVADEKFCETTIGCKDPAQGQLLKELMQTPNFRITVVQEVDTVEICGALKNVVAVGAGFCDGLGFGDNTKAAVIRLGLMEMIAFAKLFCSGPVSSATFLESCGVADLITTCYGGRNRKVAEAFARTGKSIEQLEKELLNGQKLQGPETARELYSILQHKGLVDKFPLFMAVYKVCYEGQPVGEFIHCLQNHPEHM

35-48 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 10% Glycerol, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.