1. Recombinant Proteins
  2. Viral Proteins
  3. Influenza Viruses Proteins
  4. Hemagglutinin-Neuraminidase
  5. Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His)

Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His)

Cat. No.: HY-P77389
Handling Instructions

Hemagglutinin-neuraminidase is a single viral protein that has both hemagglutinin and neuraminidase activities. Hemagglutinin neuraminidase protein plays a key role in viral infection. It attaches the virus to a cell receptor containing sialic acid, initiating the infection process. Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His) is the recombinant Virus-derived Hemagglutinin-neuraminidase protein, expressed by Sf9 insect cells , with N-His labeled tag.

For research use only. We do not sell to patients.

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Description

Hemagglutinin-neuraminidase is a single viral protein that has both hemagglutinin and neuraminidase activities. Hemagglutinin neuraminidase protein plays a key role in viral infection. It attaches the virus to a cell receptor containing sialic acid, initiating the infection process. Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His) is the recombinant Virus-derived Hemagglutinin-neuraminidase protein, expressed by Sf9 insect cells , with N-His labeled tag.

Background

Hemagglutinin-neuraminidase is a single viral protein that has both hemagglutinin and neuraminidase activities. Hemagglutinin neuraminidase protein plays a key role in viral infection. It attaches the virus to a cell receptor containing sialic acid, initiating the infection process. When the hemagglutinin-neuraminidase protein binds to the receptor, it causes conformational changes that allow the F protein to trigger fusion between the virion and the cell membrane. This fusion event facilitates the entry of the virus into the host cell. In addition, the hemagglutinin-neuraminidase protein exhibits neuraminidase activity, which contributes to the effective transmission of the virus. By separating mature virions from glycoproteins containing neuraminidase, the hemagglutinin-neuraminidase protein enables the virus to reproduce efficiently[1][2][3].

Species

Virus

Source

Sf9 insect cells

Tag

N-His

Accession

ARB07730 (S48-T579)

Gene ID

/

Molecular Construction
N-term
His
Hemagglutinin-neuraminidase (S48-T579)
Accession # ARB07730
C-term
Synonyms
Human parainfluenza virus 4b (HPIV-4b) Hemagglutinin-neuraminidase (His)
Molecular Weight

Approximately 57.12 kDa.

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Hemagglutinin-neuraminidase Protein, HPIV-4b (sf9, His)
Cat. No.:
HY-P77389
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