1. Recombinant Proteins
  2. Viral Proteins
  3. Hendra virus Glycoprotein/GP Protein (HEK293, Fc)

Hendra virus Glycoprotein/GP Protein (HEK293, Fc)

Cat. No.: HY-P74900
SDS COA Handling Instructions

The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, Fc) is the recombinant Virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Hendra virus Glycoprotein/GP Protein (HEK293, Fc) is 534 a.a., with molecular weight of ~86.3 kDa.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
10 μg $72 In-stock
20 μg $115 In-stock
50 μg $220 In-stock
100 μg   Get quote  

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  • Biological Activity

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Description

The Hendra virus Glycoprotein/GP initiates infection by binding the virus to sialic acid-containing cell receptors. Upon binding, GP induces a conformational change, triggering fusion between the virion and cell membranes by the F protein. Hendra virus Glycoprotein/GP Protein (HEK293, Fc) is the recombinant Virus-derived Hendra virus Glycoprotein/GP protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Hendra virus Glycoprotein/GP Protein (HEK293, Fc) is 534 a.a., with molecular weight of ~86.3 kDa.

Background

The Hendra virus Glycoprotein/GP plays a pivotal role in initiating infection by attaching the virus to sialic acid-containing cell receptors. Upon binding to the receptor, glycoprotein G induces a conformational change that facilitates the triggering of fusion between virion and cell membranes by the F protein.

Species

Virus

Source

HEK293

Tag

C-hFc

Accession

O89343 (Q71-S604)

Gene ID

1446471  [NCBI]

Molecular Construction
N-term
HeV GP (Q71-S604)
Accession # O89343
hFc
C-term
Synonyms
Hendra virus (HeV) (isolate Horse/Autralia/Hendra/1994) Glycoprotein Protein (Fc)
Molecular Weight

Approximately 86.3 kDa

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Solution.

Formulation

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

N/A.

Storage & Stability

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping

Shipping with dry ice.

Documentation

Hendra virus Glycoprotein/GP Protein (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Hendra virus Glycoprotein/GP Protein (HEK293, Fc)
Cat. No.:
HY-P74900
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