HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His)

Erb-b2 receptor tyrosine kinase 2 is a member of EGFR family. Erb-b2 receptor tyrosine kinase 2 is over-expressed in the tumors of many types of cancers. Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His) is the recombinant cynomolgus-derived HER2/CD340 protein, expressed by HEK293 , with C-His labeled tag. The total length of HER2/CD340 Protein, Cynomolgus (Biotinylated, HEK293, His) is 630 a.a., with molecular weight of 85-105 kDa.

Erb-b2 receptor tyrosine kinase 2 enables ATP binding and transmembrane receptor protein tyrosine kinase activity. Erb-b2 receptor tyrosine kinase 2 is involved in multicellular organism development, neuron differentiation, positive regulation of MAPK cascade, positive regulation of cell population proliferation, positive regulation of kinase activity, protein phosphorylation and transmembrane receptor protein tyrosine kinase signaling pathway. Erb-b2 receptor tyrosine kinase 2 is located in basal plasma membrane^[1][2][3].

Cynomolgus

HEK293

C-His

XP_005584091.2 (T23-T652)

/

85-105 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.