HSP10/EPF Protein, Human/Mouse (His-Avi)

The HSP10/EPF protein in collaboration with Hsp60 promotes the correct folding of the input protein and, under stressful conditions in the mitochondrial matrix, prevents misfolding while promoting the refolding and correct assembly of the unfolded polypeptide. The increased expression of HSP10 protein can inhibit the apoptosis of astrocytoma cells and is associated with poor prognosis. HSP10/EPF Protein, Human/Mouse (His-Avi) is the recombinant human, mouse-derived HSP10/EPF protein, expressed by E. coli , with C-Avi, N-His labeled tag.

Heat shock 10 kDa protein 1 (Hsp10), also known as chaperone protein 10 or Early pregnancy factor (EPF), is a protein encoded by the human HSPE1 gene. The homolog in E. coli is GroES, which is a chaperone protein that usually works in conjunction with GroEL. The HSP10/EPF protein in collaboration with Hsp60 promotes the correct folding of the input protein and, under stressful conditions in the mitochondrial matrix, prevents misfolding while promoting the refolding and correct assembly of the unfolded polypeptide. The increased expression of HSP10 protein can inhibit the apoptosis of astrocytoma cells and is associated with poor prognosis^[1][2][3].

Human; Mouse

E. coli

N-Avi;N-His

A0A8C2NRB8/XP_005676362 (A2-D102)

102173048  [NCBI]

13.70 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.