ICAM-2/CD102 Protein, Human (HEK293, His-Fc)

ICAM-2/CD102 protein belongs to the ICAM family of the immunoglobulin superfamily and may be involved in immune responses and cell interactions. This is consistent with the family's established role in immune processes. ICAM-2/CD102 Protein, Human (HEK293, His-Fc) is the recombinant human-derived ICAM-2/CD102 protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of ICAM-2/CD102 Protein, Human (HEK293, His-Fc) is 199 a.a., with molecular weight of 85-95 kDa.

ICAM-2/CD102 protein is a member of the immunoglobulin superfamily and is specifically categorized within the ICAM family. This designation signifies its likely involvement in immune responses and cellular interactions, consistent with the family's established role in immunological processes. As part of the immunoglobulin superfamily, ICAM-2/CD102 may engage in complex interactions contributing to immune regulation. Further exploration is warranted to elucidate the specific functions and implications of ICAM-2/CD102 within the broader context of the immunoglobulin superfamily, shedding light on its role in modulating immune responses and cellular adhesion.

Determined by its ability to support the adhesion of PMA-stimulated jurkat cells to plates pre-coated with ICAM-2. The ED₅₀ for this effect is 1.348 μg/mL, corresponding to a specific activity is 7.42×10^2 units/mg.

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  Determined by its ability to support the adhesion of PMA-stimulated jurkat cells to plates pre-coated with ICAM-2. The ED₅₀ for this effect is 1.348 μg/ml, corresponding to a specific activity is 7.42×10² units/mg.

Human

HEK293

C-hFc;C-His

Q6FHE2/NP_000864.2 (K25-Q223)

3384  [NCBI]

KVFEVHVRPKKLAVEPKGSLEVNCSTTCNQPEVGGLETSLDKILLDEQAQWKHYLVSNISHDTVLQCHFTCSGKQESMNSNVSVYQPPRQVILTLQPTLVAVGKSFTIECRVPTVEPLDSLTLFLFRGNETLHYETFGKAAPAPQEATATFNSTADREDGHRNFSCLAVLDLMSRGGNIFHKHSAPKMLEIYEPVSDSQ

85-95 kDa

Greater than 95% as determined by reducing SDS-PAGE

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.