IGSF11 Protein, Mouse (HEK293, His)

IGSF11 (Immunoglobulin superfamily member 11) operates as a cell adhesion molecule by engaging in homophilic interactions, thereby facilitating cell-to-cell adhesion. Additionally, IGSF11 is implicated in the stimulation of cell growth, suggesting a role in cellular proliferation and potentially contributing to regulatory pathways involved in cellular development and maintenance. IGSF11 Protein, Mouse (HEK293, His) is the recombinant mouse-derived IGSF11 protein, expressed by HEK293 , with C-His labeled tag. The total length of IGSF11 Protein, Mouse (HEK293, His) is 218 a.a., with molecular weight of 38-42 kDa.

IGSF11 (Immunoglobulin Superfamily Member 11), also known as SynCAM3 (Synaptic Cell Adhesion Molecule 3), is a cell adhesion molecule that plays a key role in mediating cell-cell interactions through homophilic binding, where it interacts with identical molecules on adjacent cells. This homophilic interaction suggests its involvement in processes related to cell adhesion, which are critical for various physiological functions such as tissue development and maintenance. Additionally, there is evidence to suggest that IGSF11 stimulates cell growth, as indicated by similarity to other proteins with known growth-promoting functions. The dual role of IGSF11 in cell adhesion and growth regulation underscores its significance in cellular processes and highlights its potential impact on tissue development and homeostasis. Ongoing research may further uncover additional details about the precise mechanisms and functions of IGSF11.

Mouse

HEK293

C-His

P0C673 (L23-V240)

207683  [NCBI]

38-42 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.