2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. Interleukin & Receptors
  5. IL-16
  6. IL-16 Protein, Human (His)

IL-16 Protein, Human (His)

Cat. No.: HY-P73169
Handling Instructions

IL-16 Protein, a cytokine, regulates immunity and inflammation. It controls the activation and movement of immune cells like T cells and monocytes. Understanding IL-16 Protein's functions helps study immune responses and develop treatments for inflammatory and autoimmune disorders. IL-16 Protein, Human (His) is the recombinant human-derived IL-16 protein, expressed by E. coli , with N-His labeled tag.

For research use only. We do not sell to patients.

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50 μg   Get quote  
100 μg   Get quote  

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Description

IL-16 Protein, a cytokine, regulates immunity and inflammation. It controls the activation and movement of immune cells like T cells and monocytes. Understanding IL-16 Protein's functions helps study immune responses and develop treatments for inflammatory and autoimmune disorders. IL-16 Protein, Human (His) is the recombinant human-derived IL-16 protein, expressed by E. coli , with N-His labeled tag.
Background

IL-16, a multifunctional cytokine, elicits a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Additionally, it primes CD4+ T-cells for responsiveness to IL-2 and IL-15, and induces the expression of interleukin-2 receptor in T-lymphocytes. Functioning as a ligand for CD4, IL-16 plays a key role in cellular interactions and immune modulation. Beyond its immunomodulatory functions, IL-16 may serve as a scaffolding protein that anchors ion channels in the cell membrane, contributing to its diverse cellular effects.
Species

Human
Source

E. coli
Tag

N-His
Accession

AAC12732.1 (P2-S130)
Gene ID
Molecular Construction
N-term
His
IL-16 (P2-S130)
Accession # AAC12732.1
C-term
Synonyms
Pro-interleukin-16; Interleukin-16; IL-16; LCF
Molecular Weight

Approximately 15.3 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

IL-16 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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