IL-22 Protein, Cynomolgus (HEK293, His)

IL-22 Protein, a member of the IL-10 family, stands out for its divergence. This crucial cytokine plays a central role in immune responses and inflammation. IL-22 promotes activation and recruitment of immune cells like Th2 cells, mast cells, and eosinophils to inflammation sites. Primarily secreted by epithelial and endothelial cells, IL-22 acts through its receptor, stimulating the production of pro-inflammatory cytokines and chemokines. Implicated in diseases like asthma, allergies, and autoimmune disorders, IL-22 holds promise as a therapeutic target for immune response modulation. IL-22 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-22 protein, expressed by HEK293, with C-His labeled tag. The total length of IL-22 Protein, Cynomolgus (HEK293, His) is 146 a.a., with molecular weight of 32-42 kDa.

IL-22 Protein belongs to the IL-10 family and is recognized for its significant divergence from other family members. This protein functions as a vital cytokine involved in numerous immune responses and inflammatory processes. IL-22 plays a crucial role in promoting the activation and recruitment of immune cells, including T-helper 2 (Th2) cells, mast cells, and eosinophils, to sites of inflammation. It is primarily secreted by epithelial and endothelial cells and exerts its effects through the IL-22 receptor. Upon binding, IL-22 stimulates the production of various pro-inflammatory cytokines and chemokines. Notably, IL-22 has been implicated in a wide range of diseases, such as asthma, allergic diseases, and autoimmune disorders, underscoring its significance as a potential therapeutic target for modulating immune responses.

Cynomolgus

HEK293

C-His

G7PHZ7 (A34-I179)

102129310  [NCBI]

32-42 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.