IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His)

IL-2R gamma/CD132 Protein, a common subunit for interleukin receptors, likely collaborates with IL15RA in stimulating neutrophil phagocytosis by IL15. It is shared among IL2, IL4, IL7, IL15, IL21, and possibly IL13 receptors. IL-2R gamma interacts with SHB upon interleukin stimulation and also interacts with IL9. IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-2R gamma/CD132 protein, expressed by HEK293 , with C-His labeled tag. The total length of IL-2R gamma/CD132 Protein, Cynomolgus (HEK293, His) is 232 a.a., with molecular weight of 50-68 kDa.

IL-2R gamma/CD132 protein serves as a common subunit for receptors of various interleukins, including IL2, IL4, IL7, IL15, IL21, and likely IL13. Likely in association with IL15RA, it plays a role in stimulating neutrophil phagocytosis by IL15. The gamma subunit, essential for diverse interleukin receptor complexes, interacts with SHB upon interleukin stimulation and also engages with IL9. Through these interactions, IL-2R gamma/CD132 contributes to the intricate network of signaling events associated with interleukin-mediated immune responses, highlighting its central role in immune modulation and cellular activities.

Cynomolgus

HEK293

C-His

Q38JL2 (L23-N254)

641338  [NCBI]

50-68 kDa

Greater than 95% as determined by Tris-Bis PAGE

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.