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  4. INSL6 Protein, Human (HEK293, His)

INSL6 Protein, Human (HEK293, His)

Cat. No.: HY-P76455
COA Handling Instructions

The INSL6 protein plays a crucial role in sperm development and fertilization, highlighting its importance in male reproductive biology. Its potential function in promoting sperm development and successful fertilization emphasizes its importance in reproductive physiology. INSL6 Protein, Human (HEK293, His) is the recombinant human-derived INSL6 protein, expressed by HEK293 , with C-His labeled tag. The total length of INSL6 Protein, Human (HEK293, His) is 178 a.a., with molecular weight of ~22.1 KDa.

For research use only. We do not sell to patients.

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Size Price Stock Quantity
Free Sample   Apply now
2 μg $30 In-stock
10 μg $75 In-stock
50 μg $215 In-stock
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  • Biological Activity

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Description

The INSL6 protein plays a crucial role in sperm development and fertilization, highlighting its importance in male reproductive biology. Its potential function in promoting sperm development and successful fertilization emphasizes its importance in reproductive physiology. INSL6 Protein, Human (HEK293, His) is the recombinant human-derived INSL6 protein, expressed by HEK293 , with C-His labeled tag. The total length of INSL6 Protein, Human (HEK293, His) is 178 a.a., with molecular weight of ~22.1 KDa.

Background

The INSL6 protein appears to play a crucial role in sperm development and fertilization, implying its involvement in key processes essential for reproductive success. The recognition of its potential function in these intricate stages of male reproductive biology underscores its significance in facilitating the development and maturation of sperm, as well as contributing to the successful fertilization of ova. The precise mechanisms by which INSL6 operates in these processes remain an area of interest, reflecting its potential as a key player in reproductive physiology.

Species

Human

Source

HEK293

Tag

C-6*His

Accession

Q9Y581/NP_009110.2 (R21-F198)

Gene ID
Molecular Construction
N-term
INSL6 (R21-F198)
Accession # Q9Y581/NP_009110.2
His
C-term
Synonyms
Insulin-like peptide INSL6; Relaxin/insulin-like factor 1; INSL6; RIF1
AA Sequence

RELSDISSARKLCGRYLVKEIEKLCGHANWSQFRFEEETPFSRLIAQASEKVEAYSPYQFESPQTASPARGRGTNPVSTSWEEAVNSWEMQSLPEYKDKKGYSPLGKTREFSSSHNINVYIHENAKFQKKRRNKIKTLSNLFWGHHPQRKRRGYSEKCCLTGCTKEELSIACLPYIDF

Molecular Weight

Approximately 28-40 kDa due to the glycosylation.

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder.

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Storage & Stability

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

INSL6 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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INSL6 Protein, Human (HEK293, His)
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HY-P76455
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