IVD Protein, Mouse (sf9, His)

IVD protein, a vital component of the leucine catabolic pathway, facilitates the transformation of isovaleryl-CoA/3-methylbutanoyl-CoA into 3-methylbut-2-enoyl-CoA. This reaction acts as an intermediate step. Moreover, IVD protein demonstrates some capacity to oxidize saturated short-chain acyl-CoA thioesters like pentanoyl-CoA, hexenoyl-CoA, and butenoyl-CoA, albeit to a lesser degree. IVD Protein, Mouse (sf9, His) is the recombinant mouse-derived IVD protein, expressed by Sf9 insect cells , with N-His labeled tag. The total length of IVD Protein, Mouse (sf9, His) is 394 a.a., with molecular weight of ~45.3 kDa.

The IVD protein plays a crucial role in the leucine (Leu) catabolic pathway by catalyzing the conversion of isovaleryl-CoA/3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA. This reaction serves as an intermediate step in the pathway. Additionally, the IVD protein exhibits the ability to catalyze the oxidation of other saturated short-chain acyl-CoA thioesters such as pentanoyl-CoA, hexenoyl-CoA, and butenoyl-CoA, although to a lesser extent.

Mouse

Sf9 insect cells

N-His

Q9JHI5 (H31-R424)

56357  [NCBI]

Approximately 45.3 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.