KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi)

KIR3DL3/CD158z, on natural killer cells, potentially inhibits NK cell activity, contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating NK cell functions and maintaining immune homeostasis. KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived KIR3DL3/CD158z protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of KIR3DL3/CD158z Protein, Human (Biotinylated, HEK293, His-Avi) is 297 a.a., with molecular weight of 45-50 kDa.

KIR3DL3, present on natural killer cells, acts as a receptor that potentially inhibits NK cell activity, thereby contributing to the prevention of cell lysis. This regulatory role underscores the significance of KIR3DL3 in modulating the functions of NK cells and maintaining immune homeostasis.

Human B7-H7, hFc Tag captured on CM5 Chip via Protein A can bind Biotinylated Human KIR3DL3, His-Avi Tag with an affinity constant of 0.35 μM as determined in SPR assay (Biacore T200).

Human

HEK293

C-Avi;C-His

Q8N743 (E26-L322)

115653  [NCBI]

45-50 kDa

Greater than 95% as determined by Tris-Bis PAGE.

Lyophilized powder.

Lyophilized from a 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, 0.2 M L-Arginine, pH 8.2. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.