2. Recombinant Proteins
  3. CD Antigens
  4. Macrophage CD Proteins
  5. LAIR-2/CD306
  6. LAIR2 Protein, Human (HEK293, His)

LAIR2 Protein, Human (HEK293, His)

Cat. No.: HY-P72527
Handling Instructions

Leukocyte-associated immunoglobulin-like receptor 2 is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 Protein, Human (HEK293, His) is the recombinant human-derived LAIR2 protein, expressed by HEK293 , with C-6*His labeled tag.

For research use only. We do not sell to patients.

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Description

Leukocyte-associated immunoglobulin-like receptor 2 is expressed as a soluble receptor exhibiting high affinity for various collagen molecules to which it binds in a hydroxyproline-dependent manner. LAIR2 Protein, Human (HEK293, His) is the recombinant human-derived LAIR2 protein, expressed by HEK293 , with C-6*His labeled tag.
Background

Leukocyte-associated immunoglobulin-like receptor 2 is a member of the immunoglobulin superfamily. Leukocyte-associated immunoglobulin-like receptor 2 is a soluble receptor that may play roles in both inhibition of collagen-induced platelet aggregation and vessel formation during placental implantation. Leukocyte-associated immunoglobulin-like receptor 2 maps to a region of 19q13.4, termed the leukocyte receptor cluster, which contains 29 genes in the immunoglobulin superfamily[1][2][3].
Species

Human
Source

HEK293
Tag

C-6*His
Accession

Q6ISS4-1 (Q22-P152)
Gene ID
Molecular Construction
N-term
LAIR2 (Q22-P152)
Accession # Q6ISS4-1
6*His
C-term
Synonyms
Leukocyte-Associated Immunoglobulin-Like Receptor 2; LAIR-2; CD306
AA Sequence

QEGALPRPSISAEPGTVISPGSHVTFMCRGPVGVQTFRLEREDRAKYKDSYNVFRLGPSESEARFHIDSVSEGNAGLYRCLYYKPPGWSEHSDFLELLVKESSGGPDSPDTEPGSSAGTVPGTEASGFDAP

Molecular Weight

Approximately 20 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

LAIR2 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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