MAB21L2 Protein, Human (His)

MAB21L2 protein, encoded by the MAB21L2 gene, is similar to the C. elegans MAB-21 gene, involved in neural fate determination. It is primarily found in the nucleus and occasionally in the cytoplasm, potentially playing a role in neural development. MAB21L2 Protein, Human (His-ZZ) is the recombinant human-derived MAB21L2 protein, expressed by E. coli , with N-His labeled tag.

The MAB21L2 gene shares similarity with the C. elegans MAB-21 cell fate-determining gene, known as a downstream target of transforming growth factor-beta signaling. Implications suggest its potential involvement in neural development. The encoded protein, primarily nuclear with occasional cytoplasmic localization, is believed to play a role in cellular processes related to neural fate determination.

Human

E. coli

N-6*His

Q9Y586/NP_006430 (M1-L359)

10586  [NCBI]

MIAAQAKLVYQLNKYYTERCQARKAAIAKTIREVCKVVSDVLKEVEVQEPRFISSLSEIDARYEGLEVISPTEFEVVLYLNQMGVFNFVDDGSLPGCAVLKLSDGRKRSMSLWVEFITASGYLSARKIRSRFQTLVAQAVDKCSYRDVVKMIADTSEVKLRIRERYVVQITPAFKCTGIWPRSAAQWPMPHIPWPGPNRVAEVKAEGFNLLSKECYSLTGKQSSAESDAWVLQFGEAENRLLMGGCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECEKHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLFQGKPHSALESAAKQTWRLAREILTNPKSLDKL

Approximately 42 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.