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  5. MAK Protein, Human (Sf9, His, GST)

MAK Protein, Human (Sf9, His, GST)

Cat. No.: HY-P701797
Handling Instructions

MAK Protein, vital for ciliary length regulation, ensures photoreceptor survival by phosphorylating FZR1 in a cell cycle-dependent manner. It coactivates AR transcription and potentially aids spermatogenesis, with a possible role in maintaining chromosomal stability in prostate cancer cells. MAK Protein, Human (Sf9, His, GST) is the recombinant human-derived MAK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAK Protein, Human (Sf9, His, GST) is 622 a.a., .

For research use only. We do not sell to patients.

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Description

MAK Protein, vital for ciliary length regulation, ensures photoreceptor survival by phosphorylating FZR1 in a cell cycle-dependent manner. It coactivates AR transcription and potentially aids spermatogenesis, with a possible role in maintaining chromosomal stability in prostate cancer cells. MAK Protein, Human (Sf9, His, GST) is the recombinant human-derived MAK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of MAK Protein, Human (Sf9, His, GST) is 622 a.a., .
Background

MAK Protein is crucial for the regulation of ciliary length and is essential for the prolonged survival of photoreceptors. It phosphorylates FZR1 in a cell cycle-dependent manner and participates in the transcriptional coactivation of AR. Additionally, MAK may contribute to spermatogenesis and could play a role in maintaining chromosomal stability in prostate cancer cells.
Species

Human
Source

Sf9 insect cells
Tag

N-8*His;N-GST
Accession

P20794 (N2-R623)
Gene ID

4117
Molecular Construction
N-term
8*His-GST
MAK (N2-R623)
Accession # P20794
C-term
Synonyms
MAK; Serine/threonine-protein kinase MAK; Male germ cell-associated kinase
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

MAK Protein, Human (Sf9, His, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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