MARCO Protein, Human (HEK293, His)

MARCO Protein, a pattern recognition receptor (PRR), binds both Gram-positive and Gram-negative bacteria, facilitating unopsonized particle binding by alveolar macrophages. It also interacts with the secretoglobin SCGB3A2. Forming disulfide-linked homotrimer structures, MARCO Protein's trimers assemble into larger oligomers, providing an expansive surface area for interactions with substantial ligands. MARCO Protein, Human (HEK293, His) is the recombinant human-derived MARCO protein, expressed by HEK293 , with N-His labeled tag. The total length of MARCO Protein, Human (HEK293, His) is 116 a.a., with molecular weight of 14-20 kDa.

MARCO Protein is a pattern recognition receptor (PRR) that can bind both Gram-positive and Gram-negative bacteria. It also plays a role in binding unopsonized particles by alveolar macrophages. Additionally, MARCO Protein is capable of binding to the secretoglobin SCGB3A2. It forms a homotrimer structure that is disulfide-linked, and these trimers can assemble into larger oligomers, creating a large surface area suitable for interacting with very large ligands.

Human

HEK293

N-His

Q9UEW3 (S405-V520)

8685  [NCBI]

14-20 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.