MEPE/OF45 Protein, Mouse (HEK293, His)

MEPE/OF45 Protein, pivotal in regulating renal phosphate and uric acid excretion, influences bone mineralization in osteoblasts and chondrocytes, with notable effects on craniofacial structures. Its role in dental pulp stem cell proliferation is significant. MEPE/OF45's interaction with PHEX, mediated by its ASARM motif, is zinc-dependent, adding complexity to its regulatory functions. MEPE/OF45 Protein, Mouse (HEK293, His) is the recombinant mouse-derived MEPE/OF45 protein, expressed by HEK293 , with C-His labeled tag. The total length of MEPE/OF45 Protein, Mouse (HEK293, His) is 417 a.a., with molecular weight of 45-60 kDa.

MEPE/OF45 protein plays a pivotal role in the regulation of renal phosphate and uric acid excretion. Its influence extends to the intricate processes of bone mineralization, affecting both osteoblasts and chondrocytes. MEPE/OF45's impact on the mineralization of the extracellular matrix is particularly notable in craniofacial structures, including teeth, bone, and cartilage. Moreover, it contributes to the proliferation of dental pulp stem cells. The protein's interaction with PHEX, mediated by its ASARM motif, is contingent on zinc, adding a layer of complexity to its regulatory functions.

Mouse

HEK293

C-His

Q8K4L6 (A25-D441)

94111  [NCBI]

45-60 kDa

Greater than 95% as determined by Tris-Bis PAGE.

<1 EU/μg, determined by LAL method.