Mesothelin Protein, Rat (HEK293, His)

Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating cell interactions. Additionally, Megakaryocyte-potentiating factor (MPF) enhances megakaryocyte colony formation, indicating its involvement in the development of these specialized blood cell colonies. Mesothelin Protein, Rat (HEK293, His) is the recombinant rat-derived Mesothelin protein, expressed by HEK293 , with C-10*His labeled tag. The total length of Mesothelin Protein, Rat (HEK293, His) is 303 a.a., with molecular weight of 43-50 kDa.

Mesothelin Protein, in its membrane-anchored forms, is implicated in cellular adhesion, suggesting a potential role in mediating interactions between cells. Additionally, Megakaryocyte-potentiating factor (MPF) has been associated with the enhancement of megakaryocyte colony formation, indicating its involvement in processes related to the development of these specialized blood cell colonies.

Measured by its binding ability in a functional ELISA. Immobilized Rat Mesothelin at 2 μ g/mL can bind Human MUC16 , the EC₅₀ is 7.561-12.47 ng/m L.

Rat

HEK293

C-10*His

XP_032768340 (D298-S600)

116908979  [NCBI]

43-50 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.