MMP-10 Protein, Human (P. pastoris, His)

MMP-10 protein is a member of the matrix metalloproteinase family and plays a crucial role in extracellular matrix remodeling by promoting the degradation of various substrates. As a protease, MMP-10 is involved in tissue homeostasis, wound healing, and inflammatory responses. MMP-10 Protein, Human (P. pastoris, His) is the recombinant human-derived MMP-10 protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of MMP-10 Protein, Human (P. pastoris, His) is 378 a.a., with molecular weight of 45 kDa.

TSPO, initially characterized as the peripheral-type benzodiazepine receptor, exhibits the ability to bind protoporphyrin IX, suggesting a potential role in porphyrin and heme transport. Beyond benzodiazepines, TSPO can also bind isoquinoline carboxamides. Its involvement in cholesterol transport across mitochondrial membranes and potential contributions to lipid metabolism have been documented, although its precise physiological role remains a subject of debate. While some reports suggest it is dispensable for steroid hormone biosynthesis, indicating controversy in its functional implications, TSPO interacts with proteins such as TSPOAP1, MOST-1, and may also engage with STAR, highlighting its versatile molecular interactions.

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

P. pastoris

N-6*His

P09238 (F99-C476)

4319  [NCBI]

FSSFPGMPKWRKTHLTYRIVNYTPDLPRDAVDSAIEKALKVWEEVTPLTFSRLYEGEADIMISFAVKEHGDFYSFDGPGHSLAHAYPPGPGLYGDIHFDDDEKWTEDASGTNLFLVAAHELGHSLGLFHSANTEALMYPLYNSFTELAQFRLSQDDVNGIQSLYGPPPASTEEPLVPTKSVPSGSEMPAKCDPALSFDAISTLRGEYLFFKDRYFWRRSHWNPEPEFHLISAFWPSLPSYLDAAYEVNSRDTVFIFKGNEFWAIRGNEVQAGYPRGIHTLGFPPTIRKIDAAVSDKEKKKTYFFAADKYWRFDENSQSMEQGFPRLIADDFPGVEPKVDAVLQAFGFFYFFSGSSQFEFDPNARMVTHILKSNSWLHC

45 kDa

Greater than 90% as determined by reducing SDS-PAGE.

Lyophilized powder.

Lyophilized from a 0.2 μm filtered solution of 10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.