MRPL44 Protein, Human (sf9, His)

MRPL44 protein is an important component of the 39S subunit of mitochondrial ribosomes. MRPL44 Protein, Human (sf9, His) is the recombinant human-derived MRPL44 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of MRPL44 Protein, Human (sf9, His) is 332 a.a., with molecular weight of ~40 kDa.

MRPL44 is a vital component of the 39S subunit of the mitochondrial ribosome, where it likely plays a role in the assembly and stability of nascent mitochondrial polypeptides as they exit the ribosome. Within the mitochondrial large ribosomal subunit (mt-LSU), MRPL44 contributes to the structural integrity and function of mature mammalian 55S mitochondrial ribosomes, which consist of a small (28S) and a large (39S) subunit. The 28S small subunit harbors a 12S ribosomal RNA (12S mt-rRNA) and 30 distinct proteins, while the 39S large subunit includes a 16S rRNA (16S mt-rRNA) and a copy of mitochondrial valine transfer RNA (mt-tRNA(Val)), which plays a crucial structural role. In total, the 39S large subunit comprises 52 diverse proteins, underscoring MRPL44's essential contribution to mitochondrial ribosome assembly and function.

Human

Sf9 insect cells

C-His

Q9H9J2 (M1-S332)

65080  [NCBI]

Approximately 40 kDa

Greater than 85% as determined by reducing SDS-PAGE

<1 EU/μg, determined by LAL method.