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  5. MSRB3 Protein, Human (HEK293, Fc)

MSRB3 Protein, Human (HEK293, Fc)

Cat. No.: HY-P76500
Handling Instructions

MSRB3 Protein, with a unique ability to catalyze methionine sulfoxide reduction, plays a crucial role in the auditory system. Isoform 2 of MSRB3 is deemed essential for normal hearing, highlighting its significance in auditory function. MSRB3 Protein, Human (HEK293, Fc) is the recombinant human-derived MSRB3 protein, expressed by HEK293, with C-hFc labeled tag. The total length of MSRB3 Protein, Human (HEK293, Fc) is 156 a.a., with molecular weight of ~43.7 KDa.

For research use only. We do not sell to patients.

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Description

MSRB3 Protein, with a unique ability to catalyze methionine sulfoxide reduction, plays a crucial role in the auditory system. Isoform 2 of MSRB3 is deemed essential for normal hearing, highlighting its significance in auditory function. MSRB3 Protein, Human (HEK293, Fc) is the recombinant human-derived MSRB3 protein, expressed by HEK293, with C-hFc labeled tag. The total length of MSRB3 Protein, Human (HEK293, Fc) is 156 a.a., with molecular weight of ~43.7 KDa.
Background

MSRB3, a protein with the distinctive ability to catalyze the reduction of both free and protein-bound methionine sulfoxide to methionine, stands out for its crucial role in the auditory system. Specifically, isoform 2 of MSRB3 is deemed essential for normal hearing, underscoring its significance in auditory function.
Species

Human
Source

HEK293
Tag

C-hFc
Accession

Q8IXL7-2 (G26-D181)
Gene ID
Molecular Construction
N-term
MSRB3 (G26-D181)
Accession # Q8IXL7-2
hFc
C-term
Synonyms
Methionine-R-sulfoxide reductase B3; MSRB3
Molecular Weight

Approximately 43.7 kDa.
Purity

Greater than 85% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

MSRB3 Protein, Human (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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